REGIONAL NERVE BLOCKS FOR RELIEVING POSTOPERATIVE PAIN IN ARTHROSCOPIC ROTATOR CUFF REPAIR



Binding of Macrolide Antibiotics Leads to Ribosomal Selection against Specific Substrates Based on Their Charge and Size

Macrolide antibiotic Dog Toys binding to the ribosome inhibits catalysis of peptide bond formation between specific donor and acceptor substrates.Why particular reactions are problematic for the macrolide-bound ribosome remains unclear.Using comprehensive mutational analysis and biochemical experiments with synthetic substrate analogs, we find that

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